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Today's
Featured Articles:
Does your Water Supply contain Drugs or Toxins
Scientists have discovered Pharmaceutical Drugs and Toxins in the Water Supply, Are you drinking this potentially dangerous cocktail.
Water treatment plants are set up to eliminate certain types of waste materials, such as pesticides, herbicides and heavy metals from the water supply. They cannot however cope, neither are they equipped to deal with pharmaceuticals, as you will probably know, up to 90% of drugs that are taken in to our bodies, is eliminated by the kidneys and urine, so whatever passes through our bodies, eventually end up back at the water treatment plant and then in to ...
Author: Alfred Jones
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Bio-Rhythm Disruption Frequency Identifier for Human Intentions
It appears we have found many identifiers for Bio-Metrics to identify people. In this new age of International Terrorism with bad guys trying to get Pilot’s Licenses, HazMat Driver’s Licenses, get onto airlines, step onto buses and sneak over our borders we need a fool proof system. Currently we use fingerprints to identify criminals and those who hold important positions. Some of the newest forms of security include retina scans, voice prints, palms, DNA, Implanted RFID Chips, etc. We have devices, which can see thru trucks, pick up the scent of bio-weapons that use heat to pick-up illegal ...
Author: Lance Winslow
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| Genetics News:
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.
Publication Date: 2005 Dec 19 PMID: 16365161Authors: Ikenouchi, J. - Furuse, M. - Furuse, K. - Sasaki, H. - Tsukita, S. - Tsukita, S.Journal: J Cell BiolFor epithelia to function as barriers, the intercellular space must be sealed. Sealing two adjacent cells at bicellular tight junctions (bTJs) is well described with the discovery of the claudins. Yet, there are still barrier weak points at tricellular contacts, where three cells join together. In this study, we identify tricellulin, the first integral membrane protein that is concentrated at the vertically oriented TJ strands of tricellular contacts. When tricellulin expression was suppressed with RNA interference, the epithelial barrier was compromised, and tricellular contacts and bTJs were disorganized. These findings indicate the critical function of tricellulin for formation of the epithelial barrier.
Site-specific biotinylation of RNA molecules by transcription using unnatural base pairs.
Publication Date: 2005 PMID: 16113238Authors: Moriyama, K. - Kimoto, M. - Mitsui, T. - Yokoyama, S. - Hirao, I.Journal: Nucleic Acids ResDirect site-specific biotinylation of RNA molecules was achieved by specific transcription mediated by unnatural base pairs. Unnatural base pairs between 2-amino-6-(2-thienyl)purine (denoted by s) and 2-oxo(1H)pyridine (denoted by y), or 2-amino-6-(2-thiazolyl)purine (denoted as v) and y specifically function in T7 transcription. Using these unnatural base pairs, the substrate of biotinylated-y (Bio-yTP) was selectively incorporated into RNA, opposite s or v in the DNA templates, by T7 RNA polymerase. This method was applied to the immobilization of an RNA aptamer on sensor chips, and the aptamer accurately recognized its target protein. This direct site-specific biotinylation will provide a tool for RNA-based biotechnologies.
Nucleotide analogues to investigate RNA structure and function.
Publication Date: 2005 Dec PMID: 16242990Authors: Das, S. R. - Fong, R. - Piccirilli, J. A.Journal: Curr Opin Chem BiolRNA plays an essential cellular role in nearly every aspect of the transmission and expression of genetic information, including regulatory roles that have significance for cellular development. Access to RNA bearing synthetic modifications has allowed biological chemists to probe deep into the inner workings of cellular processes. Here, we describe recent advances in harnessing the power of nucleotide analogues to obtain mechanistic and biological insights into RNA structure, function and dynamics.
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Garlic - Join Me And I´ll Show You Why Garlic Can Save Your Life
Are you worried yet about your health? Are you anxious about your heart, or about the possibility of contracting cancer? If so, you are not alone, and your concerns are quite valid. Cancer and heart disease are today’s major killers, and as of now, we are yet to find a safe and effective drug, that can prevent these diseases. Some will argue that taking one or two aspirins a day can reduce the risk of heart disease, and it saddens me to see how many people are doing this, because I know the problems brought by aspirin over use, if these people knew about the long term damage caused by this ...
Author: Charles Silverman
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Here are a few more
sites I've chosen if you'd like to read more and do more research:
Integrated DNA Technologies
D. (2004) Sequence-specific inhibition of small RNA function. PLoS Biology, 2:465. Click Here to go to the RNAi Catalog Page Click Here to go to the LNA Catalog Page Click Here to go to the AntiSense.
UM Biophysics Faculty Hashim M Al-Hashimi
Edu Al-Hashimi Lab Our laboratory applies solution state NMR spectroscopy to investigate the molecular basis of RNA function in processes ranging from gene expression (e.G. Transcriptional activation.
Promega eNotes - Citations
Complexes. -TNT Systems Telomerase RNA function in recombinant Tetrahymena telomerase. -TNT Systems Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.
Minerals Are Key - brazillivecoral.com
Manganese is necessary for RNA function. Excessive manganese intake can produce brain dysfunction, Parkinsonian dementia, intellectual impairment, central nervous system destruction, violent behavior.
TIME Magazine: The Secret of Life
Baltimore With his first experiment on the subject, he shattered existing theories of DNA and RNA function By Leon Jaroff Posted Sunday, February 9, 2002; 10:31 a.M. EST It was not until the late.
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Selling With Principles -- NOT Plungers
For most of us, selling is against our natures. We were taught as
children to be polite, courteous, and respecting of others. (Well, at
least some of us were anyway.)
The problem is, selling seems to go against those principles. Notice I
said selling 'seems' to go against the polite, courteous side of
ourselves. In actuality, however, only bad salesmanship is overly
aggressive, obtrusive, and just plain not nice.
However, if your just starting out, it can be difficult to find a way to
make your point and offer your product without feeling like you're
r ...
Author: Joe Bingham
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Computer Game on Mars; Design for Communication Device
Powering up hand held wireless devices in the field for Business Uses, Educational Issues, Monitoring Sensors for Security Purposes or Blue Force Tracking for military troops in the field for net-centric warfare is possible even in the most remote locations can be possible using simple principles which will provide small amounts of energy. There are a few new innovative ways to do this, which appear to have been overlooked. One is to have an inflatable sphere or beach ball with inner reflective skin, which is reflective on the inside, which can take on light waves or UV from the sun or ener ...
Author: Lance Winslow
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